ABSTRACT
Aim: Our study aims to assess the mean pupil size under scotopic, mesopic, photopic and dynamic conditions in patients with PXS. Methodology: This study was performed in Ophthalmology Clinic at İstanbul Bakırköy Dr.Sadi Konuk Training and Research Hospital. Fourty-six patients with PXS and 46 age and sex matched controls were included in the prospective study. The subjects were allowed at least 3 minute to adapt to the lighting condition in the room. Pupil diameters were measured with infrared (IR) pupillometer integrated within CSO Sirius Corneal Topographer (Costruzione Strumenti Oftalmici S.r.l,Italy ) by the same examiner. The measurements were taken in scotopic, mesopic, photopic and dynamic conditions. Statistical analyses were evaluated. Results: Mean pupil diameter were significantly lower in the PXS group than control group for all measurements. Scotopic and mesopic pupil size were significantly lower in the PXS group than control group (p=0.0001). Also photopic and dynamic pupil size were significantly lower in the PXS group than control group (p=0.014, p=0.013). Conclusion: The results suggest that pupillary light response in patients with PXS significantly was affected not only in scotopic and mesopic conditions but also in photopic and dynamic conditions.